advances in interdisciplinary endocrinology

RECENT ADVANCES Advances in endocrinology

New developments in endocrinology, in common with many specialised branches of medicine, have been dominated by advances in molecular genetics. Although these investigations relate to rare single gene disorders, they have resulted in major breakthroughs in many fields of endocrinology, significantly contributing to our understanding of the cellular mechanisms of hormone action. However it is no...

Advances in endocrinology.

To those who do not know me I should begin with a brief but relevant biography to establish my frame of reference for this topic. My personal experience in clinical endocrinology spans a period of 32 years commencing with registrar training on the St George’s Hospital rotation in 1975. Prior to this I had some general introduction to endocrinology during my undergraduate training at Guy’s Hospi...

Recent Advances in Endocrinology

Advances in endocrinology.

Molecular genetics will continue to help us to make precise diagnoses. At present, the expertise to achieve this for a specific disease is often exclusive to one unit with a research interest. It will be important to establish a coordinated approach at a supraregional level to provide molecular diagnosis for rare disorders as a fast reliable clinical service. In addition understanding the molec...

Recent Advances in Endocrinology

Clinically relevant genetic advances in endocrinology.

Significant advances in molecular genetics have enabled the genetic abnormalities associated with endocrine disorders to be identiin clinical practice in several ways, including confirmation of the clinical diagnosis; identification of asymptomatic family members who harbour the mutation and require screening for the development of early disease manifestations, thereby facilitating earlier trea...